An ultra-fast, high-resolution HPLC support tailored specifically for peptides, proteins and MS.
Method Type: HPLC & UPLC
Base Material: Non-Porous Silica
Particle Size: 1.5 µm NPS beads
Surface Chemistry: Polymeric and Monomeric C18
Molecular Weight Range: < 200 kD
Column Length: 14mm to 53mm
Column ID: 3.0mm to 4.6mm
The HPRP column design is compatible with any HPLC or UPLC instrument, delivering the separation and resolving power of HPLC—trusted for decades in small molecule analysis—into routine protein and peptide analysis laboratories.
This column is ideal for high-throughput applications, quality control laboratories, and LC/MS separations.
It’s totally non-porous nature provides for fast mass transfer kinetics and high recovery of proteins at low surface carbon loads and organic MP modifiers, facilitating easy elution and recovery of highly hydrophobic proteins.
DS-II, also known as HPRP, is unique NPS-based HPLC column designed specifically for complex protein and peptide samples. These samples usually contain detergents, chaotropes, and additives typical to protein and peptide solubilization.
small drug molecules to biomolecules Can be rapidly analyzed With ODS-I columns. With the addition of modifiers such as TEA, excellent peak shapes for many basic compounds such as TCA's can be obtained.
This is an excellent column for high-throughput and QC lab applications, as well as LC/MS separations. The end capping delivers excellent resolution and analysis speed with low peak tailing for basic drug compounds.